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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD2
All Species:
27.88
Human Site:
S614
Identified Species:
61.33
UniProt:
O14939
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14939
NP_002654.3
933
105987
S614
L
R
S
V
D
R
W
S
A
G
T
L
E
N
S
Chimpanzee
Pan troglodytes
XP_511291
924
105027
S614
L
R
S
V
D
R
W
S
A
G
T
L
E
N
S
Rhesus Macaque
Macaca mulatta
XP_001117754
892
101098
S573
L
R
S
V
D
R
W
S
A
G
T
L
E
N
S
Dog
Lupus familis
XP_536610
854
96426
T556
D
P
S
E
P
A
A
T
Q
P
P
T
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P97813
933
106150
S614
L
R
S
V
D
R
W
S
A
G
T
L
E
N
S
Rat
Rattus norvegicus
P70498
933
106019
S614
L
R
S
V
D
R
W
S
A
G
T
L
E
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422793
1072
123414
S751
I
R
S
A
A
D
W
S
A
G
I
K
Y
H
E
Frog
Xenopus laevis
NP_001129642
1039
119219
S717
L
R
S
A
A
D
W
S
A
G
I
K
Y
H
E
Zebra Danio
Brachydanio rerio
XP_694649
927
106849
S607
L
R
S
V
D
R
W
S
A
G
T
C
E
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194932
825
94056
I527
H
Q
A
Y
I
H
A
I
N
N
S
K
H
Y
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
G707
S
V
S
Q
W
S
A
G
T
S
Q
P
E
D
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
92.1
77.2
N.A.
90
89.5
N.A.
N.A.
48.8
50.9
59.2
N.A.
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
97.2
93.7
80.7
N.A.
93.8
93.1
N.A.
N.A.
63.3
66.2
73.5
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
100
100
6.6
N.A.
100
93.3
N.A.
N.A.
40
46.6
86.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
53.3
53.3
93.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
19
19
10
28
0
73
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
0
0
55
19
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
64
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
73
0
0
0
10
0
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
0
10
28
0
% H
% Ile:
10
0
0
0
10
0
0
10
0
0
19
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% K
% Leu:
64
0
0
0
0
0
0
0
0
0
0
46
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
0
0
0
37
0
% N
% Pro:
0
10
0
0
10
0
0
0
0
10
10
10
0
0
0
% P
% Gln:
0
10
0
10
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
73
0
0
0
55
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
91
0
0
10
0
73
0
10
10
0
0
10
64
% S
% Thr:
0
0
0
0
0
0
0
10
10
0
55
10
0
0
0
% T
% Val:
0
10
0
55
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
73
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
19
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _